Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 22 Researches
7.7
USERS' SCORE
Good
Based on 515 Reviews
8.1
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Biotin
10,000 mcg
33,333%
Top Medical Research Studies
9
We encountered a case of a woman suffering from short bowel syndrome, who faced significant hair loss due to biotin deficiency while on home parenteral nutrition. After starting oral biotin supplementation of 10 mg/day for three weeks, we observed that her serum biotin levels increased, leading to noticeable new hair growth and resolution of other symptoms. Further intravenous biotin treatment maintained her on multivitamins that include biotin, preventing any future deficiency symptoms. This case highlights the importance of addressing biotin levels for hair health and overall well-being.
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9.5
We explored the effects of biotin treatment on hair loss through a case study of a girl diagnosed with biotinidase deficiency. Despite having no notable family history of the condition, her symptoms included problematic dermatitis, yellow hair, and alopecia.
After identifying low levels of biotinase and significant metabolic increases, the girl was found to have two specific mutations in her BTD gene linked to this deficiency. Following the diagnosis, we observed a clear response to biotin supplementation, with an initial dosage of 20 mg per day.
Remarkably, her dermatitis improved within a month, and her hair color returned to normal after three months of treatment. These findings suggest that biotin replacement therapy can have significant positive outcomes in cases related to biotinidase deficiency, connecting biotin to effective hair restoration.
After identifying low levels of biotinase and significant metabolic increases, the girl was found to have two specific mutations in her BTD gene linked to this deficiency. Following the diagnosis, we observed a clear response to biotin supplementation, with an initial dosage of 20 mg per day.
Remarkably, her dermatitis improved within a month, and her hair color returned to normal after three months of treatment. These findings suggest that biotin replacement therapy can have significant positive outcomes in cases related to biotinidase deficiency, connecting biotin to effective hair restoration.
Read More
2
We investigated the effectiveness of biotin as a treatment for hair loss through a literature review focused on available studies. Our search led us to three specific studies that were relevant to the question of whether oral biotin truly supports hair growth or improves hair quality.
One of these studies stood out due to its rigorous design—a double-blind, placebo-controlled trial—but interestingly, it found no significant difference between participants taking biotin and those receiving a placebo when it came to hair growth. The other two studies we examined involved specific groups of patients, such as those on isotretinoin and women who had undergone sleeve gastrectomy. Despite their unique perspectives, these studies were also limited by potential biases and did not provide strong evidence in favor of biotin.
Overall, while biotin has gained immense popularity as a hair supplement among the public, it appears that if one hopes to find robust scientific support for its effectiveness, the evidence is lacking. High-quality research does not substantiate the common belief that biotin can significantly benefit hair health.
One of these studies stood out due to its rigorous design—a double-blind, placebo-controlled trial—but interestingly, it found no significant difference between participants taking biotin and those receiving a placebo when it came to hair growth. The other two studies we examined involved specific groups of patients, such as those on isotretinoin and women who had undergone sleeve gastrectomy. Despite their unique perspectives, these studies were also limited by potential biases and did not provide strong evidence in favor of biotin.
Overall, while biotin has gained immense popularity as a hair supplement among the public, it appears that if one hopes to find robust scientific support for its effectiveness, the evidence is lacking. High-quality research does not substantiate the common belief that biotin can significantly benefit hair health.
Read More
Most Useful Reviews
8
Effective for hair loss
210 people found this helpful
Biotin is a fantastic aid for hair loss. I took half a tablet, as 10,000 mcg seemed excessive. Yet, from just half the dosage, I noticed results.
Read More
7.5
Overall health boost
155 people found this helpful
This vitamin, one of the B vitamins, aids carbohydrate, fat, and protein metabolism. Biotin, as a coenzyme, contributes to energy production, and besides benefiting hair health, it helps reduce hair loss and positively impacts overall health.
Read More
9
Very effective biotin
140 people found this helpful
Biotin is excellent for hair loss. This particular version comes in strawberry chewable tablets.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 22 Researches
7.7
- All Researches
9.5
Biotin serum shows promising results
We investigated the effectiveness of the Dr. SKS Hair Booster Serum, which contains biotin and other micronutrients, for treating androgenetic alopecia in both men and women. This open-label study included 1,000 participants across multiple clinics in India who received the serum through mesotherapy or derma roller techniques for six months.
During the study, we closely monitored various indicators of hair health, including the amount of hair loss, hair growth rates, and overall hair density changes. Our findings revealed a significant reduction in hair fall and a notable improvement in hair density after treatment. Interestingly, 95% of participants reported satisfaction with the results after six months.
It’s important to note that while biotin is a key ingredient in the serum, the study did not isolate its effects from the other micronutrients, making it challenging to definitively attribute the positive outcomes solely to biotin. No major adverse effects were reported, suggesting a safe treatment profile.
Overall, the study demonstrated that the Dr. SKS Hair Booster Serum could be a viable option for those struggling with hair loss, providing promising results in the context of androgenetic alopecia.
During the study, we closely monitored various indicators of hair health, including the amount of hair loss, hair growth rates, and overall hair density changes. Our findings revealed a significant reduction in hair fall and a notable improvement in hair density after treatment. Interestingly, 95% of participants reported satisfaction with the results after six months.
It’s important to note that while biotin is a key ingredient in the serum, the study did not isolate its effects from the other micronutrients, making it challenging to definitively attribute the positive outcomes solely to biotin. No major adverse effects were reported, suggesting a safe treatment profile.
Overall, the study demonstrated that the Dr. SKS Hair Booster Serum could be a viable option for those struggling with hair loss, providing promising results in the context of androgenetic alopecia.
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9.5
Alopecia areata improvement with tofacitinib
We explored the effectiveness of tofacitinib, a treatment showing promise for alopecia areata (AA), particularly in cases that have proven resistant to other therapies. In one instance, a young adult male with resistant AA had not responded to treatments like oral and topical steroids, minoxidil, and oral troxasalen.
In this study, he received tofacitinib at a dose of 5 mg twice a day along with a biotin supplement. Remarkably, hair regrowth was noted just one month into the treatment, and by the three-month mark, over 90% of his hair had regrown. It’s worth mentioning that no side effects were recorded during the treatment period.
Our findings suggest that while biotin was administered alongside tofacitinib, its specific contributions to hair regrowth outcomes cannot be distinctly isolated. Thus, further research would be necessary to clarify the role of biotin in hair loss treatments.
In this study, he received tofacitinib at a dose of 5 mg twice a day along with a biotin supplement. Remarkably, hair regrowth was noted just one month into the treatment, and by the three-month mark, over 90% of his hair had regrown. It’s worth mentioning that no side effects were recorded during the treatment period.
Our findings suggest that while biotin was administered alongside tofacitinib, its specific contributions to hair regrowth outcomes cannot be distinctly isolated. Thus, further research would be necessary to clarify the role of biotin in hair loss treatments.
Read More
9.5
We explored the effects of biotin treatment on hair loss through a case study of a girl diagnosed with biotinidase deficiency. Despite having no notable family history of the condition, her symptoms included problematic dermatitis, yellow hair, and alopecia.
After identifying low levels of biotinase and significant metabolic increases, the girl was found to have two specific mutations in her BTD gene linked to this deficiency. Following the diagnosis, we observed a clear response to biotin supplementation, with an initial dosage of 20 mg per day.
Remarkably, her dermatitis improved within a month, and her hair color returned to normal after three months of treatment. These findings suggest that biotin replacement therapy can have significant positive outcomes in cases related to biotinidase deficiency, connecting biotin to effective hair restoration.
After identifying low levels of biotinase and significant metabolic increases, the girl was found to have two specific mutations in her BTD gene linked to this deficiency. Following the diagnosis, we observed a clear response to biotin supplementation, with an initial dosage of 20 mg per day.
Remarkably, her dermatitis improved within a month, and her hair color returned to normal after three months of treatment. These findings suggest that biotin replacement therapy can have significant positive outcomes in cases related to biotinidase deficiency, connecting biotin to effective hair restoration.
Read More
9
We explored the effectiveness of Dr. SKS Hair Booster Serum, which contains biotin among other ingredients, in treating female pattern hair loss (FPHL) in women diagnosed with polycystic ovary syndrome (PCOS). Our study included 1,000 females aged 25-50 who experienced hair loss classified as Ludwig grades I and II.
Over six months, participants received the serum through injections in the scalp. We employed various assessment techniques, such as photography and microscopic evaluations, to measure changes in hair growth, thickness, and overall health before and after treatment.
After the treatment period, we observed significant improvements in several key hair parameters, including hair shaft diameter and terminal hair counts, as well as a decrease in unwanted hair. Notably, while biotin is a component of the formula, the study could not isolate its specific effects on hair loss due to the combination of multiple active ingredients.
Importantly, no adverse events were reported during the study, suggesting that Dr. SKS Hair Booster Serum is a safe option for those seeking to manage FPHL associated with PCOS. Overall, this study highlights a promising approach to treating hair loss in this specific patient population.
Over six months, participants received the serum through injections in the scalp. We employed various assessment techniques, such as photography and microscopic evaluations, to measure changes in hair growth, thickness, and overall health before and after treatment.
After the treatment period, we observed significant improvements in several key hair parameters, including hair shaft diameter and terminal hair counts, as well as a decrease in unwanted hair. Notably, while biotin is a component of the formula, the study could not isolate its specific effects on hair loss due to the combination of multiple active ingredients.
Importantly, no adverse events were reported during the study, suggesting that Dr. SKS Hair Booster Serum is a safe option for those seeking to manage FPHL associated with PCOS. Overall, this study highlights a promising approach to treating hair loss in this specific patient population.
Read More
9
We conducted a study to evaluate how effective biotin, when combined with dexpanthenol injections, is at treating diffuse hair loss. In our research, fifty participants suffering from this condition were divided into two groups to receive six weekly injections of different brands of the treatment—one from Pars Behvarzan and the other from Bayer.
After completing the treatment, we assessed the results through various methods like hair fall counts and hair density tests at one and eight weeks post-treatment. We were pleased to find that both treatments significantly helped in reducing hair loss and improving hair density. Specifically, the hair fall count showed remarkable improvement in both groups, while hair density also saw beneficial changes.
Interestingly, while both treatments were effective, we did notice that the Bayer group had a better improvement in the terminal-to-vellus hair ratio when compared to the Pars group at both follow-ups. Overall, our findings suggest that these injections of biotin and dexpanthenol are effective and safe for individuals experiencing diffuse hair loss, offering a reliable option for those looking to enhance their hair health.
After completing the treatment, we assessed the results through various methods like hair fall counts and hair density tests at one and eight weeks post-treatment. We were pleased to find that both treatments significantly helped in reducing hair loss and improving hair density. Specifically, the hair fall count showed remarkable improvement in both groups, while hair density also saw beneficial changes.
Interestingly, while both treatments were effective, we did notice that the Bayer group had a better improvement in the terminal-to-vellus hair ratio when compared to the Pars group at both follow-ups. Overall, our findings suggest that these injections of biotin and dexpanthenol are effective and safe for individuals experiencing diffuse hair loss, offering a reliable option for those looking to enhance their hair health.
Read More
User Reviews
USERS' SCORE
Good
Based on 515 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
8
Effective for hair loss
210 people found this helpful
Biotin is a fantastic aid for hair loss. I took half a tablet, as 10,000 mcg seemed excessive. Yet, from just half the dosage, I noticed results.
Read More
7.5
Overall health boost
155 people found this helpful
This vitamin, one of the B vitamins, aids carbohydrate, fat, and protein metabolism. Biotin, as a coenzyme, contributes to energy production, and besides benefiting hair health, it helps reduce hair loss and positively impacts overall health.
Read More
9
Very effective biotin
140 people found this helpful
Biotin is excellent for hair loss. This particular version comes in strawberry chewable tablets.
Read More
9
Notable improvement noted
110 people found this helpful
This biotin works effectively at the optimal dosage. Initially, I took 1000 mg, thinking 300% of the daily norm would yield results, but it didn’t. However, at 10,000 mg, I definitely experienced an improvement. If you are dealing with hair loss, I recommend this supplement.
Read More
8
Less shedding noticed
102 people found this helpful
I took it to combat hair loss, and surprisingly, it works. My hair is shedding less; I take one capsule daily after meals.
Read More
Frequently Asked Questions
9
Quick results observed
5 people found this helpful
Initially, I tried biotin to address hair loss and found that the price in local pharmacies was quite high. This type of biotin is affordable, allowing continued use. It is pleasantly sweet, dissolving quickly in the mouth without needing water. It's very gentle on the stomach, suitable for those who find swallowing pills difficult. After 10 days, I observed a 20 to 30 percent reduction in hair loss following childbirth. I was quite pleased with the rapid results.
7.5
Reduces hair loss
5 people found this helpful
As always, iHerb is exceptional. The delivery was quick and intact. I purchased biotin to prevent hair loss after experiencing hair fall due to Covid. Within two weeks, I saw results—my hair falls out less and feels thicker, and the tasty vitamin doesn’t require water.
9
Effective hair treatment
5 people found this helpful
For those who suffer from hair loss, the best vitamin is feme hair, though it is quite expensive. A better option is NATROL's biotin products, which contain similar ingredients and yield equal or improved results at a more reasonable price. With continued use, you will notice longer hair and stronger nails, as breakage and shedding will diminish. After two and a half months of use, I was very satisfied with the outcome. The tablets taste of strawberry, are somewhat hard, and should be consumed with 2 litres of water daily. I take one 10,000 dosage pill after breakfast. This product is beneficial for both women and men facing hair loss.
10
Stops hair loss
3 people found this helpful
With a large dosage, my hair loss halted quickly, and I’ve seen a lot of new hair growth.
9
Significantly decreased loss
5 people found this helpful
I felt very comfortable with Biotin Natural. The quality is excellent, and my skin has improved greatly, becoming more vibrant. My hair has grown longer, and hair loss has decreased significantly. It also strengthens nails, and most importantly, it tastes deliciously sweet. I've repurchased it many times, always delighted with the results.
9
Notable improvement noted
110 people found this helpful
This biotin works effectively at the optimal dosage. Initially, I took 1000 mg, thinking 300% of the daily norm would yield results, but it didn’t. However, at 10,000 mg, I definitely experienced an improvement. If you are dealing with hair loss, I recommend this supplement.
7.5
Impressive results achieved
4 people found this helpful
The order arrived in Ukraine within 10 days. After nearly a month of taking this biotin, my hair has become shiny, more manageable, and I’ve noticed significantly less hair loss. I also take omega 3-6-9 and astaxanthin alongside biotin. I’m seeing results and would recommend it to others.
9
Effective for hair health
4 people found this helpful
This supplement was created for our health and beauty, particularly for stimulating hair growth and maintaining skin and nail health. I took it for two months when I began experiencing hair loss, alongside a hair growth spray. I'm impressed by the results and highly recommend it for its natural strawberry flavour and absence of artificial additives.
10
Highly effective
2 people found this helpful
This product is very pleasant to take and remarkably effective against hair loss. I highly recommend the 10,000 biotin from the same brand for strong results.
8
Effective for hair loss
210 people found this helpful
Biotin is a fantastic aid for hair loss. I took half a tablet, as 10,000 mcg seemed excessive. Yet, from just half the dosage, I noticed results.
2
We investigated the effectiveness of biotin as a treatment for hair loss through a literature review focused on available studies. Our search led us to three specific studies that were relevant to the question of whether oral biotin truly supports hair growth or improves hair quality.
One of these studies stood out due to its rigorous design—a double-blind, placebo-controlled trial—but interestingly, it found no significant difference between participants taking biotin and those receiving a placebo when it came to hair growth. The other two studies we examined involved specific groups of patients, such as those on isotretinoin and women who had undergone sleeve gastrectomy. Despite their unique perspectives, these studies were also limited by potential biases and did not provide strong evidence in favor of biotin.
Overall, while biotin has gained immense popularity as a hair supplement among the public, it appears that if one hopes to find robust scientific support for its effectiveness, the evidence is lacking. High-quality research does not substantiate the common belief that biotin can significantly benefit hair health.
One of these studies stood out due to its rigorous design—a double-blind, placebo-controlled trial—but interestingly, it found no significant difference between participants taking biotin and those receiving a placebo when it came to hair growth. The other two studies we examined involved specific groups of patients, such as those on isotretinoin and women who had undergone sleeve gastrectomy. Despite their unique perspectives, these studies were also limited by potential biases and did not provide strong evidence in favor of biotin.
Overall, while biotin has gained immense popularity as a hair supplement among the public, it appears that if one hopes to find robust scientific support for its effectiveness, the evidence is lacking. High-quality research does not substantiate the common belief that biotin can significantly benefit hair health.
7
Biotin showed no significant benefits
We explored the effects of biotin on hair growth through a randomized, crossover clinical trial that involved different treatment groups. The trial compared 5% topical minoxidil alone, 5 mg oral biotin alone, and a combination of both treatments to see how they impacted hair growth in men.
Despite the inclusion of biotin in the study, the outcomes did not show a significant benefit for hair growth when biotin was used alone. The results suggest that while topical minoxidil may exhibit effective hair growth stimulation, the isolated effects of oral biotin in conjunction with or without minoxidil warrant further study to clarify its actual role.
Consequently, we can conclude that although biotin is often promoted as a hair growth aid, this particular research did not find strong evidence to support its effectiveness on its own, particularly when compared to the known benefits of topical minoxidil.
Despite the inclusion of biotin in the study, the outcomes did not show a significant benefit for hair growth when biotin was used alone. The results suggest that while topical minoxidil may exhibit effective hair growth stimulation, the isolated effects of oral biotin in conjunction with or without minoxidil warrant further study to clarify its actual role.
Consequently, we can conclude that although biotin is often promoted as a hair growth aid, this particular research did not find strong evidence to support its effectiveness on its own, particularly when compared to the known benefits of topical minoxidil.
7
Biotin's limited efficacy on hair loss
We examined the potential of biotin as a treatment for hair loss. While the study included biotin, it also considered other treatments, which made it a bit challenging to pinpoint the specific effectiveness of biotin alone.
The findings suggested that biotin may not be the cure-all some hope for. Its impact on hair loss was somewhat limited and didn't indicate a significant benefit when evaluated.
Overall, the results indicate that more focused research is needed to truly assess how biotin affects hair growth independently.
The findings suggested that biotin may not be the cure-all some hope for. Its impact on hair loss was somewhat limited and didn't indicate a significant benefit when evaluated.
Overall, the results indicate that more focused research is needed to truly assess how biotin affects hair growth independently.
8
We investigated the effects of biotin as part of a combination therapy aimed at tackling hair loss, particularly in those suffering from androgenic alopecia (AGA). This condition often leads to thinning hair and changes in the hair growth cycle, a problem linked to the hormone dihydrotestosterone (DHT), especially in men.
Each of the key components studied—arginine, arterial extract, and biotin tripeptide-1—was combined with low-level light therapy (LLLT) and was successful in enhancing essential cellular functions like mitochondrial performance, cell growth, and collagen production in skin cells.
Importantly, we noted that biotin worked alongside other substances, and we could see significant improvements in hair follicles. We observed reductions in inflammatory markers and increases in products that promote hair growth. This combined approach holds promise as a comprehensive solution to AGA, effectively addressing both hormonal and cell-based factors contributing to hair loss.
Each of the key components studied—arginine, arterial extract, and biotin tripeptide-1—was combined with low-level light therapy (LLLT) and was successful in enhancing essential cellular functions like mitochondrial performance, cell growth, and collagen production in skin cells.
Importantly, we noted that biotin worked alongside other substances, and we could see significant improvements in hair follicles. We observed reductions in inflammatory markers and increases in products that promote hair growth. This combined approach holds promise as a comprehensive solution to AGA, effectively addressing both hormonal and cell-based factors contributing to hair loss.
8
Biotin aids hair and skin health
We explored the effects of biotin supplementation in patients undergoing treatment with isotretinoin for acne. In this study, we monitored 60 participants, dividing them into two groups. Both groups received isotretinoin, but one group also took an additional 10 mg of biotin daily. Our goal was to see how this biotin could influence hair health and overall skin condition during treatment.
After four months, we noted significant changes in the group taking biotin. Specifically, the proportion of hair in the anagen (growing) phase increased, while the percentage of hair in the telogen (resting) phase decreased. This suggests that biotin may support hair regrowth during isotretinoin therapy. Additionally, we observed that the skin hydration remained stable in the biotin group, compared to a notable decline in hydration for those not taking the supplement.
Overall, our findings indicate that adding biotin can help mitigate some side effects associated with isotretinoin, especially regarding hair health and skin moisture retention. While it may not be a miracle cure for hair loss, biotin definitely plays a beneficial role in this context.
After four months, we noted significant changes in the group taking biotin. Specifically, the proportion of hair in the anagen (growing) phase increased, while the percentage of hair in the telogen (resting) phase decreased. This suggests that biotin may support hair regrowth during isotretinoin therapy. Additionally, we observed that the skin hydration remained stable in the biotin group, compared to a notable decline in hydration for those not taking the supplement.
Overall, our findings indicate that adding biotin can help mitigate some side effects associated with isotretinoin, especially regarding hair health and skin moisture retention. While it may not be a miracle cure for hair loss, biotin definitely plays a beneficial role in this context.
References
- Yelich A, Jenkins H, Holt S, Miller R. Biotin for Hair Loss: Teasing Out the Evidence. J Clin Aesthet Dermatol. 2024;17:56.
- Qiu S, Pan Z, Jiang X, Lv G, Feng A, et al. The synergistic effect of phototherapy and active substances on hair growth. J Photochem Photobiol B. 2024;259:113008. doi:10.1016/j.jphotobiol.2024.113008
- Valentim FO, Miola AC, Miot HA, Schmitt JV. Efficacy of 5% topical minoxidil versus 5 mg oral biotin versus topical minoxidil and oral biotin on hair growth in men: randomized, crossover, clinical trial. An Bras Dermatol. 2024;99:581. doi:10.1016/j.abd.2023.07.008
- Khare S. Efficacy of Dr. SKS Hair Booster Serum in the Treatment of Female Pattern Alopecia in Patients With PCOS: An Open-Label, Non-randomized, Prospective Study. Cureus. 2023;15:e44941. doi:10.7759/cureus.44941
- Tr P, Ts R, K SK, Prasanna H. A Comparative Study of Topical Procapil With Platelet-Rich Plasma Therapy Versus Topical Redensyl, Saw Palmetto, and Biotin With Platelet-Rich Plasma Therapy in the Treatment of Androgenetic Alopecia. Cureus. 2023;15:e38696. doi:10.7759/cureus.38696
- Khare S. The Efficacy and Safety of Dr. SKS Hair Booster Serum (a Cocktail of Micronutrients and Multivitamins) in Adult Males and Females With Androgenetic Alopecia: An Open-Label, Non-randomized, Prospective Study. Cureus. 2023;15:e37424. doi:10.7759/cureus.37424
- Sahay G. Resistant Alopecia Areata Treated with Tofacitinib. Int J Trichology. 2022;14:181. doi:10.4103/ijt.ijt_63_22
- Jo H, Kim SY, Kang BH, Baek C, Kwon JE, et al. Cicaria, a Novel Strain Derived from the Human Microbiome, and Its Efficacy as a Treatment for Hair Loss. Molecules. 2022;27. doi:10.3390/molecules27165136
- Samadi A, Ketabi Y, Firooz R, Firooz A. Efficacy of intramuscular injections of biotin and dexpanthenol in the treatment of diffuse hair loss: A randomized, double-blind controlled study comparing two brands. Dermatol Ther. 2022;35:e15695. doi:10.1111/dth.15695
- Starace M, Gurioli C, Carpanese MA, Bruni F, Piraccini BM, et al. Short anagen syndrome: A case series and algorithm for diagnosis. Pediatr Dermatol. 2021;38:1157. doi:10.1111/pde.14750
- Aksac SE, Bilgili SG, Yavuz GO, Yavuz IH, Aksac M, et al. Evaluation of biophysical skin parameters and hair changes in patients with acne vulgaris treated with isotretinoin, and the effect of biotin use on these parameters. Int J Dermatol. 2021;60:980. doi:10.1111/ijd.15485
- Yang Y, Yang JY, Chen XJ. Biotinidase deficiency characterized by skin and hair findings. Clin Dermatol. 2020;38:477. doi:10.1016/j.clindermatol.2020.03.004
- Şen O, Türkçapar AG. Hair Loss After Sleeve Gastrectomy and Effect of Biotin Supplements. J Laparoendosc Adv Surg Tech A. 2021;31:296. doi:10.1089/lap.2020.0468
- Marotta JC, Patel G, Carvalho M, Blakeney S. Clinical Efficacy of a Topical Compounded Formulation in Male Androgenetic Alopecia: Minoxidil 10%, Finasteride 0.1%, Biotin 0.2%, and Caffeine Citrate 0.05% Hydroalcoholic Solution. Int J Pharm Compd. 2020;24:69.
- Piraccini BM, Berardesca E, Fabbrocini G, Micali G, Tosti A. Biotin: overview of the treatment of diseases of cutaneous appendages and of hyperseborrhea. G Ital Dermatol Venereol. 2019;154:557. doi:10.23736/S0392-0488.19.06434-4
- Sant'Anna Addor FA, Donato LC, Melo CSA. Comparative evaluation between two nutritional supplements in the improvement of telogen effluvium. Clin Cosmet Investig Dermatol. 2018;11:431. doi:10.2147/CCID.S173082
- Hayashi A, Mikami Y, Miyamoto K, Kamada N, Sato T, et al. Intestinal Dysbiosis and Biotin Deprivation Induce Alopecia through Overgrowth of Lactobacillus murinus in Mice. Cell Rep. 2017;20:1513. doi:10.1016/j.celrep.2017.07.057
- Castro-Gago M, Pérez-Gay L, Gómez-Lado C, Castiñeiras-Ramos DE, Otero-Martínez S, et al. The influence of valproic acid and carbamazepine treatment on serum biotin and zinc levels and on biotinidase activity. J Child Neurol. 2011;26:1522. doi:10.1177/0883073811409227
- Castro-Gago M, Gómez-Lado C, Eirís-Puñal J, Díaz-Mayo I, Castiñeiras-Ramos DE. Serum biotinidase activity in children treated with valproic acid and carbamazepine. J Child Neurol. 2010;25:32. doi:10.1177/0883073809336118
- Schulpis KH, Karikas GA, Tjamouranis J, Regoutas S, Tsakiris S. Low serum biotinidase activity in children with valproic acid monotherapy. Epilepsia. 2001;42:1359.
- Khalidi N, Wesley JR, Thoene JG, Whitehouse WM, Baker WL. Biotin deficiency in a patient with short bowel syndrome during home parenteral nutrition. JPEN J Parenter Enteral Nutr. 1984;8:311.
